2026 NFL Week 1 Betting Guide: Odds, Trends, Schedule & Promos

The 2026 NFL season has arrived, and the  Week 1 NFL schedule  is filled with intriguing storylines and top matchups as part of a 13-game Sunday slate, offering options to utilize the  top promo codes  for NFL Week 1. Sunday features matchups such as Vikings vs. Packers, Commanders vs. Eagles and Cowboys vs. Giants in Week 1 games that are sure to have a significant impact on the final standings. Giants wide receiver Malik Nabers (knee) is questionable for Sunday's showdown against the Cowboys. Our Week 1  NFL betting  guide highlights many of the top NFL betting trends, previews every game on the Week 1 NFL schedule and provides step-by-step instructions to claim the latest NFL promos and boost your bankroll.  Claim the latest DraftKings promo code, where new users get $200 in bonus bets after making a $5 wager :

The Washington Commanders have been on a roller coaster the last three years. They had the No. 2 pick to draft Jayden Daniels and then went 12-5 in 2024. However, Daniels played only seven games last year, and the Commanders lost 12. Now, the Commanders open the 2026 season against a consistent winner in the Eagles. Philadelphia went 11-6 last year for its fourth straight double-digit win season. The Commanders are 5.5-point underdogs on the road in the latest Week 1 NFL odds for a 4:25 p.m. ET start.

The Sunday slate concludes with an NFC East matchup as well, with the New York Giants hosting the Dallas Cowboys. Both teams had losing records last year but have offensive potential for a turnaround season, and in the Giants' case, a new head coach in John Harbaugh. The Cowboys are 3-point favorites in the latest Cowboys vs. Giants odds.  Use the FanDuel promo code to get $350 in bonus bets for NFL games:

If you're wondering how to bet on the NFL, or where to bet on NFL Week 1, our 2026 NFL Week 1 betting guide highlights some of the best NFL promo codes, including the FanDuel promo code , DraftKings promo code and bet365 bonus code . You can use these sign-up bonuses to significantly boost your bankroll, and we'll also offer an intro to NFL wagering that gives you everything you need to know before you begin NFL betting.  Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:

How to bet on NFL Week 1

NFL action creates plenty of betting options, such as winners, spreads, totals, player props, and game props, for online sports betting apps to utilize, and those looking to bet on NFL Week 1 will have no shortage of betting markets. Online sports betting is now legal in more than 30 states, plus Washington D.C. and Puerto Rico, and it's straightforward to register for online betting sites like DraftKings, FanDuel, bet365, BetMGM, Hard Rock Bet, Fanatics Sportsbook and Caesars. With the NFL regular season finally here, top sports betting apps are offering sportsbook promos that could help you boost your bankroll ahead of one of the most wagered-on sports in America.

Bet on every NFL game by   claiming the latest DraftKings promo code, where new users get $200 in bonus bets after your first $5 wager :

2026 NFL Week 1 schedule

Sunday, Sept. 13

Saints vs. Lions (-7, 49.5), 1 p.m. ET

Buccaneers vs. Bengals (-3.5, 50.5), 1 p.m. ET

Ravens vs. Colts (+3.5, 48), 1 p.m. ET

Browns vs. Jaguars (-8.5, 40), 1 p.m. ET

Jets vs. Titans (-1.5, 38.5), 1 p.m. ET

Bills vs. Texans (+1.5, 44.5), 1 p.m. ET

Falcons vs. Steelers (-4.5, 41.5), 1 p.m. ET

Bears vs. Panthers (+3, 46.5), 1 p.m. ET

Packers vs. Vikings (-1.5, 46.5), 4:25 p.m. ET

Dolphins vs. Raiders (-3, 40.5), 4:25 p.m. ET

Cardinals vs. Chargers (-9.5, 47.5), 4:25 p.m. ET

Commanders vs. Eagles (-5.5, 44.5), 4:25 p.m. ET

Cowboys vs. Giants (+3, 48), 8:20 p.m. ET

Monday, Sept. 14

Broncos vs. Chiefs (-2.5, 43.5), 8:15 p.m. ET

NFL Week 1 game previews

Saints vs. Lions preview

Saints vs. Lions kickoff time: 1 p.m. ET on Sunday Saints vs. Lions spread: Detroit -6.5 Saints vs. Lions Over/Under: 49.5 Saints vs. Lions money line: Detroit -330, New Orleans +265

The Saints went 4-1 in their final five games last season, and after opening 1-7 with Spencer Rattler as the starting quarterback, they went 5-4 over nine games with Tyler Shough as QB1. Shough, a second-round pick in the 2025 NFL Draft, enters his first season as the full-time starter as Kellen Moore embarks on his second season as head coach. The Lions are coming off a 9-8 finish after back-to-back seasons with at least 12 wins. Detroit has had a winning record in each of its last four seasons under head coach Dan Campbell, and the Lions had the No. 4 scoring offense at 28.3 points per game last year.  Bet on the NFL by   claiming the latest DraftKings promo code, where new users get $200 in bonus bets after your first $5 wager :

Buccaneers vs. Bengals preview

Buccaneers vs. Bengals kickoff time: 1 p.m. ET Buccaneers vs. Bengals spread: Cincinnati -3.5 Buccaneers vs. Bengals Over/Under: 51.5 Buccaneers vs. Bengals money line: Cincinnati -210, Tampa Bay +176

Tampa Bay's streak of five straight NFC South titles came to an end last season in an 8-9 campaign. Quarterback Baker Mayfield was unable to reach a contract extension with the Buccaneers this offseason, so his performance in a contract year will be a significant storyline to watch this season. And this year he'll be playing without star wide receiver Mike Evans, who signed with the 49ers. The Bengals have been notoriously slow starters, losing three straight season openers before squeezing past the Browns, 17-16, last year. There's no debating the Bengals' offensive ability with Joe Burrow at quarterback, Ja'Marr Chase and Tee Higgins at receiver, and Chase Brown in the backfield. They also boosted their defense, trading their first-round pick to the Giants for Dexter Lawrence and signing defensive linemen Jonathan Allen and Boye Mafe after having the 30th-ranked scoring defense last year at 28.9 ppg allowed.  Claim the Fanatics Sportsbook promo code CBSFAN26 here to get up to $1,000 in FanCash:

Ravens vs. Colts preview

Ravens vs. Colts kickoff time: 1 p.m. ET Ravens vs. Colts spread: Baltimore -3.5 Ravens vs. Colts Over/Under: 48.5 Ravens vs. Colts money line: Baltimore -186, Indianapolis +156

The 18-year John Harbaugh era as the Ravens' head coach has come to an end, and Week 1 marks Jesse Minter's first game as Baltimore's head coach. Minter has ties to Harbaugh's brother, Jim, serving the last two years as the Chargers' defensive coach after following Jim from Michigan, where Minter also served as defensive coordinator. The Ravens should have a healthy Lamar Jackson at quarterback, a fresh Derrick Henry in the backfield, and a newly paid Zay Flowers to lead the offense. The Colts opened last season on fire, going 7-1 and winning eight of 12 games before Daniel Jones suffered a season-ending right Achilles tear. Jones is back and healthy to start Week 1, though.  Claim the Caesars Sportsbook promo code CBSDYW here and double your winnings on 10 bets :

Browns vs. Jaguars preview

Browns vs. Jaguars kickoff time: 1 p.m. ET Browns vs. Jaguars spread: Jacksonville -7.5 Browns vs. Jaguars Over/Under: 40.5 Browns vs. Jaguars money line: Jacksonville -420, Cleveland +320

Todd Monken, most recently the Ravens' offensive coordinator, takes over as Cleveland head coach with the Browns coming off a 5-12 season. The Browns will look significantly different this season, most notably due to trading reigning NFL Defensive Player of the Year Myles Garrett to the Rams. Meanwhile, the Jaguars are coming off a significant turnaround in Year 1 of the Liam Coen era. Jacksonville went 13-4 and won the AFC South last year after a 4-13 record the year before. Trevor Lawrence threw for 4,007 yards for Jacksonville, which was tied for the fifth-best scoring offense at 27.7 points per game. The Jaguars went 4-1 ATS as a home favorite last season.  Claim $365 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the promo code CBSBET365 :

Jets vs. Titans preview

Jets vs. Titans kickoff time: 1 p.m. ET Jets vs. Titans spread: Tennessee -2.5 Jets vs. Titans Over/Under: 39.5 Jets vs. Titans money line: Tennessee -134, New York +114

Geno Smith begins his second stint as the Jets' quarterback. Smith was a second-round pick by the Jets in the 2013 NFL Draft, but he was benched after going 11-18 over his first two seasons. Smith later found a mid-career resurgence in Seattle, and New York traded for him this offseason from the Raiders to lead the offense in Year 2 under head coach Aaron Glenn. However, the Jets will see a familiar face on the opposing sideline with Robert Saleh, who coached New York for three-and-a-half seasons before being fired in 2024, leading the Titans. Saleh is flanked by former Giants head coach Brian Daboll at offensive coordinator. The Titans brought in offensive reinforcements for Cam Ward, the No. 1 pick in the 2025 NFL Draft, most notably drafting Ohio State wide receiver Carnell Tate No. 4 overall in the 2026 NFL Draft.  Sign up at Hard Rock Bet and get $100 in bonus bets :

Bills vs. Texans preview

Bills vs. Texans kickoff time: 1 p.m. ET Bills vs. Texans spread: Houston -1.5 Bills vs. Texans Over/Under: 44.5 Bills vs. Texans money line: Houston -110, Buffalo -106

The Bills are the preseason favorites to win the AFC, which is one of the few things Josh Allen has yet to achieve in the NFL. Buffalo had the No. 3 scoring offense at 28.3 points per game last season. James Cook led the NFL with 1,621 rushing yards, and he's scored 32 total touchdowns over the last two seasons. Joe Brady, who was Buffalo's offensive coordinator last year, takes over for Sean McDermott as head coach for a Buffalo team that won 12 games last season, marking its seventh straight year with at least 10 victories. However, this is your classic offense vs. defense matchup, as Houston had the  No. 2 scoring defense at 17.3 points per game allowed, while allowing the fewest yards (271.9 per game). The Texans went 12-5 for their third straight double-digit win season.  Use the FanDuel promo code to get $350 in bonus bets for NFL games:

Falcons vs. Steelers preview

Falcons vs. Steelers kickoff time: 1 p.m. ET Falcons vs. Steelers spread: Pittsburgh -3 Falcons vs. Steelers Over/Under: 41.5 Falcons vs. Steelers money line: Pittsburgh -156, Atlanta +132

Tua Tagovailoa is set to start the opener in his first year in Atlanta after five seasons with the Dolphins. He'll have strong playmakers around him in running back Bijan Robinson, wide receiver Drake London and tight end Kyle Pitts. Atlanta went 8-9 last season for its eighth straight losing campaign, and Kevin Stefanski, who helped turn around the Browns at times as head coach, begins his first season with the Falcons. Meanwhile, the Steelers begin the retirement tour of Aaron Rodgers, who is paired up with his former head coach in Green Bay, Mike McCarthy. The Steelers won the AFC North at 10-7 last season for their third straight double-digit-win season. It's going to be strange seeing someone other than Mike Tomlin as head coach in Pittsburgh, as Tomlin was in charge for 19 years.  Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:

Bears vs. Panthers preview

Bears vs. Panthers kickoff time: 1 p.m. ET Bears vs. Panthers spread: Chicago -2.5 Bears vs. Panthers Over/Under: 45.5 Bears vs. Panthers money line: Chicago -152, Carolina +128

The first year of the Ben Johnson era as Chicago head coach resulted in an NFC North-champion 11-6 season. Caleb Williams, the No. 1 overall pick in the 2024 NFL Draft, threw for 3,942 yards with 27 touchdowns and seven interceptions as Chicago had the No. 9 scoring offense (25.7 ppg) on the fourth-most yards (375.7 per game). Meanwhile, the Panthers are also coming off a division title; however, they did so in an 8-9 season in the NFC South. Dave Canales enters his third year as Carolina's head coach with Bryce Young, the No.

_Originally reported by [CBS Sports](https://www.cbssports.com/betting/news/how-to-bet-on-2026-nfl-week-1-betting-guide-odds-trends-game-previews-schedule-promos-more-offers/)._