2026 College Football Week 4: Betting Guide, Odds, and Key Trends

The Week 4 college football schedule is the best we've seen yet, with six matchups between ranked opponents and a total of more than 70 games creating  college football betting  opportunities that span Thursday, Friday and Saturday. You can use matchups like Tennessee vs. Texas, Florida vs. Ole Miss and USC vs. Oregon to collect nearly $3,000 in sign-up bonuses by using the  top sportsbook promos  on some of the  best betting apps  this week.

The latest Week 4 college football odds list No. 1 Texas as a 5.5-point favorite over No. 14 Tennessee at noon ET on Saturday, and the over/under is 55.5. Our Week 4 college football betting guide will identify top college football betting trends, preview this week's biggest college football matchups, and give you detailed instructions on how to cash in on these college football betting promos.  Claim the latest DraftKings promo code, where new users get $150 in bonus bets after making a $5 wager :

Meanwhile, the latest Week 4 college football lines also list No. 21 Florida as a 3.5-point favorite at home over No. 21 Ole Miss with the over/under at 60.5. Then No. 20 Oregon is favored by 3 over No. 12 USC, with the over/under for this Big Ten battle at 62.5 points. We'll break down each of those games and nearly a dozen others in this Week 4 college football betting preview.  Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the promo code CBSBET365 :

If you're wondering how to bet on college football, or where to bet on college football Week 4, our 2026 CFB Week 4 betting guide highlights some of the best college football promo codes, including the FanDuel promo code , DraftKings promo code and bet365 bonus code .

You can use these sign-up offers to load your account with bonus bets and other new user perks. We'll also offer an intro to college football wagering that gives you everything you need to know before you begin college football betting.  Bet on college football with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:

How to bet on Week 4 college football

The Week 4 college football schedule is filled with top-25 matchups, which could make this a popular college football betting slate. Whether you are a fan of betting on winners, spreads, totals, or props, there are plenty of  sportsbook promos  from the nation's largest sportsbooks for new and existing users to utilize on the action. Online sports betting is now legal in more than 30 states, plus Washington D.C. and Puerto Rico, and with their growing prevalence, many of the top sports betting apps, such as FanDuel, DraftKings, bet365, BetMGM, Hard Rock Bet, Fanatics Sportsbook and Caesars, continue to offer strong promotions for football season. With Week 4 of the college football season here, all of these top sports betting apps are offering ways to help boost your bankroll with summer official over.

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2026 Week 4 college football odds, schedule

Thursday, Sept. 24

Liberty at Coastal Carolina (+2.5, 50.5), 7:30 p.m. ET

Friday, Sept. 25

Army at Temple (+3, 48.5), 4 p.m. ET

Howard at Rutgers (-42.5, 53.5), 7 p.m. ET

Navy at UAB (+7, 51.5), 7 p.m. ET

Northwestern at No. 5 Indiana (-21.5, 49.5), 8 p.m. ET

Clemson at California (-1.5, 50.5), 10:30 p.m. ET

Saturday, Sept. 26

Colorado State at UTSA (-13.5, 58.5), 12 p.m. ET

San Diego State at Toledo (-3, 49.5), 12 p.m. ET

UNLV at Akron (+13.5, 49.5), 12 p.m. ET

Sam Houston at Texas Tech (-34.5, 55.5), 12 p.m. ET

Texas at Tennessee (+5.5, 55.5), 12 p.m. ET

Bucknell at Pitt (-49.5, 58.5), 12 p.m. ET

Colorado at Baylor (-10, 55.5), 12 p.m. ET

Virginia Tech at Boston College (+14, 48.5), 12 p.m. ET

Wake Forest at Louisville (-12.5, 58.5), 12 p.m. ET

Illinois at Ohio State (-27.5, 53.5), 12 p.m. ET

Ball State at Kent State (-3.5, 50.5), 12 p.m. ET

South Alabama at Kentucky (-20.5, 54.5), 12:45 p.m. ET

Lindenwood at Eastern Michigan (-26.5, 49.5), 1 p.m. ET

UCLA at Maryland (+1.5, 57.5), 1:30 p.m. ET

Notre Dame at Purdue (+27.5, 57.5), 2 p.m. ET

NIU at Georgia State (-9.5, 55.5), 2 p.m. ET

Central Arkansas at Florida State (-44.5, 60.5), 3 p.m. ET

Hawaii at Wyoming (+3.5, 45.5), 3 p.m. ET

Robert Morris at Buffalo (-28.5, 44.5), 3:30 p.m. ET

William & Mary at Duke (-43.5, 62.5), 3:30 p.m. ET

Boise State at Western Michigan (+7, 53.5), 3:30 p.m. ET

UConn at Miami (Ohio) (-3.5, 48.5), 3:30 p.m. ET

Stonehill at Ohio (-37.5, 51.5), 3:30 p.m. ET

Oklahoma at Georgia (-14, 44.5), 3:30 p.m. ET

Ole Miss at Florida (-3.5, 58.5), 3:30 p.m. ET

New Mexico at New Mexico State (+11.5, 57.5), 3:30 p.m. ET

Gardner-Webb at Marshall (-26.5, 51.5), 3:30 p.m. ET

TCU at UCF (+3, 48.5), 3:30 p.m. ET

Utah at Iowa State (+7.5, 49.5), 3:30 p.m. ET

Iowa at Michigan (+5.5, 38.5), 3:30 p.m. ET

Houston at Georgia Southern (+18.5, 56.5), 4 p.m. ET

NC Central at East Carolina (-31.5, 52.5), 4 p.m. ET

Vanderbilt at Auburn (-9.5, 54.5), 4:15 p.m. ET

USF at Bowling Green (+17.5, 48.5), 5 p.m. ET

Wisconsin at Penn State (-9.5, 45), 5 p.m. ET

Nebraska at Michigan State (+5.5, 48.5), 5 p.m. ET

Delaware at Virginia (-19, 52.5), 6 p.m. ET

UIW at Texas State (-30.5, 61.5), 6 p.m. ET

LIU at FIU (-34.5, 51.5), 6 p.m. ET

James Madison at Old Dominion (+3.5, 51.5), 6 p.m. ET

Central Michigan at Miami (-41.5, 55), 6:30 p.m. ET

Louisiana at Charlotte (+10.5, 48.5), 6:30 p.m. ET

Kennesaw State at Arkansas State (-6.5, 52.5), 7 p.m. ET

Southern Miss at Tulane (-18.5, 52.5), 7 p.m. ET

Mercyhurst at WKU (-37.5, 54.5), 7 p.m. ET

South Carolina at Alabama (-12.5, 54.5), 7 p.m. ET

Kansas State at Cincinnati (+6.5, 53.5), 7 p.m. ET

Oklahoma State at West Virginia (+1.5, 60.5), 7 p.m. ET

Middle Tennessee at Jacksonville State (-8.5, 54), 7 p.m. ET

Appalachian State at NC State (-14, 55.5), 7:30 p.m. ET

HCU at North Texas (-38.5, 58.5), 7:30 p.m. ET

Arizona at Washington State (+10, 48.5), 7:30 p.m. ET

Troy at Utah State (-3, 48.5), 7:30 p.m. ET

Texas A&M at LSU (-8.5, 51.5), 7:30 p.m. ET

Oregon at USC (+3, 62.5), 7:30 p.m. ET

Missouri at Mississippi State (-6.5, 58.5), 7:45 p.m. ET

Florida Atlantic at ULM (+13.5, 57.5), 8 p.m. ET

Tulsa at Arkansas (-7, 50.5), 8 p.m. ET

Missouri State at SMU (-34.5, 59.5), 9 p.m. ET

Oregon State at UTEP (-10.5, 55.5), 9 p.m. ET

UMass at Sacramento State (+5, 48.5), 9 p.m. ET

Rice at Fresno State (-13.5, 44.5), 10 p.m. ET

Georgia Tech at Stanford (+4.5, 47.5), 10:30 p.m. ET

Air Force at Nevada (+4.5, 48.5), 10:30 p.m. ET

Minnesota at Washington (-10, 45.5), 11 p.m. ET

Temple vs. Army preview

Temple vs. Army kickoff time 4 p.m. ET (on Friday) Temple vs. Army spread Army -3 Temple vs. Army over/under 48.5 Temple vs. Army money line Temple +132, Army -157

Jeff Monken's Black Knights are coming off a bye week following a hard-fought 28-24 loss to South Florida that dropped Army to 1-1. Meanwhile, Temple is 1-2 on the season following a 49-48 loss to Toledo last week. Both programs have been dependent on the run early, with Army averaging 394 rushing yards per game and Temple averaging 221 yards on the ground. The Black Knights have had six different players score rushing TDs already and Keveun Mason (283 yards, two touchdowns) dominates the backfield work for the Owls.  Use the FanDuel promo code to get $250 in bonus bets for college football games:

UAB vs. Navy preview

UAB vs. Navy kickoff time 7 p.m. ET (on Friday) UAB vs. Navy spread Navy -7 UAB vs. Navy over/under 51.5 UAB vs. Navy money line UAB +225, Navy -279

In another matchup featuring a favored service academy, UAB hosts Navy and the circumstances are similar. The Midshipmen are 1-1 coming out of a bye week following a 38-30 loss to FAU and the Blazers are 1-2 after a 21-14 loss to Louisiana. Navy quarterback Braxton Woodson has rushed for 295 yards and four touchdowns, but he's only 6-for-17 as a passer this season. Meanwhile, UAB running back Roderick Robinson II has produced a team-leading 259 scrimmage yards and a touchdown.  Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:

Indiana vs. Northwestern preview

No. 5 Indiana vs. Northwestern kickoff time 8 p.m. ET (on Friday) No. 5 Indiana vs. Northwestern spread Indiana -21 No. 5 Indiana vs. Northwestern over/under 49.5 No. 5 Indiana vs. Northwestern money line Indiana -2041, Northwestern +1063

The defending national champions have breezed to a 3-0 start where they've outscored their opponents 145-16. However, they'll face their first power conference opponent of the season and open Big Ten play when they host Northwestern on Friday night. The Wildcats are off to a 2-0 start with convincing wins over San Diego State (34-18) and Colorado (41-7). David Braun's squad covered the spread in both of those matchups, while the Hoosiers are 0-3 against the number despite the wide scoring margin.  Claim the Caesars Sportsbook promo code CBSSPORTSBR250 here for $250 in bet resets as a new user :

Tennessee vs. Texas preview

No. 14 Tennessee vs. No. 1 Texas kickoff time Noon ET No. 14 Tennessee vs. No. 1 Texas spread Texas -5.5 No. 14 Tennessee vs. No. 1 Texas over/under 55.5 No. 14 Tennessee vs. No. 1 Texas money line Tennessee +180, Texas -217

Texas vaulted to No. 1 two weeks ago with a come-from-behind win at home over Ohio State. However, the Longhorns haven't played on the road yet, and they'll face a hostile environment on Saturday at Neyland Stadium. Tennessee starts true freshman Faizon Brandon at quarterback, but he'll be challenged by a Texas defense loaded with NFL prospects. It's the first SEC game of the season for both programs, and it's the first meeting between the schools since the 1968 Cotton Bowl.  Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook :

Ohio State vs. Illinois preview

No. 7 Ohio State vs. Illinois kickoff time Noon ET No. 7 Ohio State vs. Illinois spread Ohio State -27.5 No. 7 Ohio State vs. Illinois over/under 53.5 No. 7 Ohio State vs. Illinois money line Ohio State -4348, Illinois +1725

Ohio State took out its frustrations from the Texas game on Kent State last week with a 59-3 win to improve to 2-1. Now the Buckeyes begin Big Ten play against Illinois, which is also 2-1 on the season with the loss coming at home against Duke two weeks ago. Ohio State holds a 69-30-4 edge in the all-time series and won its first matchup with Illinois in eight years last season (34-16). The Buckeyes covered as 14.5-point favorites on the road against the Illini last season, and Ohio State is also 3-0 against the spread in 2026, while Illinois is 1-2 against the number.  Bet on college football with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:

Wake Forest vs. No. 16 Louisville preview

Wake Forest vs. No. 16 Louisville kickoff time Noon ET Wake Forest vs. No. 16 Louisville spread Louisville -12.5 Wake Forest vs. No. 16 Louisville over/under 58.5 Wake Forest vs. No. 16 Louisville money line Louisville -520, Wake Forest +390

Both Wake Forest and Louisville enter at 2-1 this season. Wake Forest is coming off a 33-20 loss to No. 5 Miami, but the Demon Deacons held the high-powered Miami offense to just one touchdown in the second half. Wake Forest opened the season with back-to-back 38-point efforts, topping Akron, 38-16, in Week 1 before defeating Purdue, 38-36, in double overtime. Louisville is coming off a 41-31 win over No. 16 SMU behind 265 rushing yards, led by Keyjuan Brown's 163 yards and two touchdowns on 16.3 yards per carry. The Cardinals opened the season hanging with now No. 4 Ole Miss in a 41-38 loss. The No. 16 Cardinals have won at least nine games in each of Jeff Brohm's first three seasons as head coach.  Sign up at Hard Rock Bet and get $100 in bonus bets :

Colorado vs. Baylor preview

Colorado vs. Baylor kickoff time Noon ET Colorado vs. Baylor spread Baylor

_Originally reported by [CBS Sports](https://www.cbssports.com/betting/news/how-to-bet-on-2026-week-4-college-football-betting-guide-odds-trends-apps-promos-previews-schedule/)._